The shoulder joint permit ate greatest mobility of any joint area carries out the importment function of stabilization for hand use. So handgrip activity is important to evaluate while assessing shoulder load in manual work. There was an association between static handgrip and shoulder muscle activity. The purpose of this study was to find out the changes of the hand grip strength according to shouter an81e. One hundred (50 female, 50 male) college adult volunteers with no known shoulder dysfunction participated subject in three positions with elbow extension: (1) shoulder $0^{circ}$ flexion (2) shoulder $90^{circ}C$ flexion (3)shoulder $180^{circ}C$ flexion. The paired t-test was used to determine the different in grip strength between right and left hand at shouter position change. All, there was significiant for all three position by right and left shoulder (p<0.001). In mon, the ANOVA results revealed not a significiant F-ratio fer all three position by right and left hand. In woman, revealed significiant (p<0.05).