This study focused on ordering factors influencing depression among late-elementary children. Subjects were 436 boys and girls enrolled in the fourth, fifth, and sixth grades of a public school. The contribution of grade, sex, 6 subtypes of stress, self-esteem, and social skills to depression was explored. The instruments were the Daily Hassles Scale, the Self-Esteem Scale, Teenage Inventory of Social Skills, and Child Depression Inventory. Results indicated that self-esteem was the most influential factor in increasing the level of depression. Next was the stress issued from friends in both males and females. There was a statistically significant difference among grades in the level of stress related to friends. The level of stress issued from parents and self-esteem among grades were marginally associated with depression. Gender differences in the level of stress from parents, friends, self-esteem, and social skills were also evident. The results were discussed in the context of the effects of subtype stress, self-esteem, and social skills on depression.