In this paper, we analyze CDMA systems using M-orthogonal spreading codes. We assume that each user one set of M-orthogonal spreading codes allocated randomaly. The effect of multiple access interference from the reference and adjacent cells is considered slowly frequency selective rayleigh fading channels. and the adjacent cells interference is considered toanalyze the system performance. We calculate bit error rate and the maximum number of users whoe can communicate simulaneously within a cell by suing Rake receiver. By comparing CDMA systemwhich transmits 1 bit/spreding code, our system shows bit error rate decreases as M increases under the same bandwidth and infromation rate.