The concentrations of air pollutants In large cities such as Pusan area have been increased every year due to the increasing of fuels consumption at factories and by vehicles as well as the gravitation of the population. In addition to the pollution sources, time and spatial variation of air pollutants concentration and meteorological factors have a great influence on the air pollution problem. Especially , its concentration is governed by wind direction, wind speed, precipitation, solar radiation, temperature, humidity and cloud amounts, etc. In this study, we have analyzed various data of meteorological factors using typical patterns of the air pressure to investigate how the concentration of air pollutants is varied with meteorological condition. Using the relationship between meteorological factors (air temperature, relative humidity, wind speed and solar radiation) and the concentration of air pollutants (SO2, O3) , experimental prediction formulas for their concentration were obtained. Therefore, these prediction formulas at each meteorological factor in a pressure pattern may be roughly used to predict the air pollutants concentration and contributed to estimate the variation of its value according to the weather condition in Pusan city.