The influence of transportation on air quality has been elevating in urban area. Air pollutants from automobiles cause primary and secondary air pollution, and need to be tightly controlled. In this study, the effect of automobile air pollutants on highway vicinity area was evaluated by the comparison of field measurement. and target was for modeling using CALINE3, NO2 was the target for this work. It was found that the concentration predicted by CALINE3 is overestimated at low wind speed and input data of wind speed requires correction. Based on the measured data, the wind speed was modified by effective wind speed equation [Ue=U+0.24·EXP(-pxU)], and there after the accuracy of CALINE3 calculation was improved neighborhood area of highway. It was also observed that weather conditions and traffic volume affect the concentration of air pollution. Finally, the NO2 effect of automobile air pollutants on the vicinity area of highway proved to be up to 400∼600m from the highway.