To clarify the anesthetic effect of acupoint injection(aquapupuncture) using general anasthetics in dogs, 18 mongrel dogs were divided into control and two experimental groups(Tian-ping+Bai-hui : Tian-ping group and San-yang-luo+Gong-sun group : San -yang- lux group). Control group was intramuscularly injected with ketamine hydrochloride, 22 mg/ kg of body weight into the thigh and experimental groups were injected into each acupoint with half volume of dosage, respectively. Clinical findings(recumbency time, induction time of anesthesia, time of head lift and standing time) and changes of vital sign(temperature, heart rate and respiration rate) were investigates at pre-anesthesia, during anesthesia and poststanding, respectively. In recumbency time San-yang-luo groupui<0.05) and Tian-ping group (p<0.05) were faster than that of control, respectively and Tian-ping group was the fastest. In induction time of anesthesia San-yang-luo group was similar to that of control, however, Tian-ping group was faster than that of control(p<O.01). In time of head lift experimental groups were slower than that of control and Tian-ping group was the slowest(p<0.05). In standing time San-yang-luo group were slight faster than that of controls but Tian-ping group was quite slower than that of contro1(p<0.05). In vital signs the changes of temperature and respiration rate were not significant between control and experimental groups, whereas heart rates were increased in during anesthesia and were decreased after standing. San-yang-luo group(p<0.05) and Tian-ping group showed increasing tendency of heart rate during anesthesia, compared with that of control, respectively. Considering above findings collectively, it was to be known that induction time of anesthesia was faster, maintenance time of anesthesia was longer and the changes of vital signs were not significant in acupoint injection using general anesthetics, compared with those of general anesthesia by intramuscular injection.