Histiocytic necrotizing lymphadenitis(NHL), or Kikuchi-Fujimoto disease, is of unknown origin that causes persistently enlarged cervical lymph nodes unresponsive to antibiotic therapy, usually in young women. Symptoms of NHL include tender cervical adenopathy, fever, weight loss, and night sweats. Laboratory studies usually reveal leukopenia and increased erythrocyte sedimentation rate. Lymph node biopsy reveals areas with frank cell necrosis, karyorrhexis, and absence of plasma cells. NHL follows a benign course, but shoud be differentiated from other diseases such as inflammatory, granulmomatous and malignant lymphadenopathies. We describe . three cases of NHL with a review of the literature.