NC machining of large screw which is usually used as a part in an extruder for injection molding is done on 3-axis turning machine, and it is very time-consuming process. Not only in machining but in preparing part program for a NC machine, it requires very long time because the shape of the screw is not easy to model when using an existing general CAD/CAM software even though it is workstation level software. In addition, tool path generation procedure for NC turning for screw shape is also very tedious one because large amount of data for cutter location point must be produced and there is no specific CAM software for the machining. In this paper. development of a CAM system for screw machining which saves the role of CAD software by use of menu driven data input system for various screw shapes is introduced.