The vaporization characteristics and spray combustion processes in the high-pressure environment are numerically investigated. This study employ the high-pressure vaporization model together with the state-of-art spray submodels. The present high-pressure vaporization model can account for transient liquid heating, circulation effect inside the droplet forced convection, Stefan flow effect, real gas effect and ambient gas solubility in the liquid droplets. Computations are carried out for the evaporating sprays, the evaporating and burning sprays, and the spray combustion processes of the turbocharged diesel engine. Numerical results indicate that the high-pressure effects are quite crucial for simulating the spray combustion processes including vaporization, spray dynamics, combustion, and pollutant formation.