Brief hypnotherapy with daily self-hypnosis was used to a 20-year-old male patient who had severe warts on the fingers of both hands for 6 years. He had had several dermatological treatments, including attempts to remove the warts with topical chemotherapy, but the warts had always recurred. During the hypnotic session, it was suggested that the warts would begin to feel cool and disappear with imaginary laser. He responded well to ideosensory suggestions and was free of the warts within 5 sessions. Inquiry after 7 months revealed that no recurrence had taken place. Finally, it is stimulating to think that harmony between mind and body involving cell-mediated immunity can intervene in conditioning the course of the skin diseases.