Tooth transposition is the phenomenon in which two teeth in the dental arch are exchanged. The tooth most frequently involved in transposition is the permanent maxillary canine, especially with the first premolar. The etiology of transposition is still an enigma. Interchange of tooth germs, migration during eruption, genetic factor, local pathologic factors may be suggested as possible etiologic factors. There are three main options for treatment, which are the extraction of one of the transposed teeth, the alignment in the transposed position, the orthodontic movement of the teeth to their correct positions. If complete transposition occurred especially in mandible, alignment of teeth in the transposed position followed by occlusal reduction and esthetic restoration is usually recommended. The presented two-case report will describe the maxillary canine to the first premolar and to lateral incisor transposition with associated peg lateralis and retained primary canines. Although alignment the transposed teeth in original position is ideal treatment, it companies many complication as root resorption, alveolar bone destruction, gingival deheisence, etc. Therefore the treatment procedures in these case was relative cost-benefit effective method to both clinician and patients.