- 중만분소환(中滿分消丸)이 생쥐의 간손상(肝損傷)에 미치는 영향(影響)
- ㆍ 저자명
- 김희철,김정상,이용운,Kim. Hee-Chul,Kim. Jung-Sang,Lee. Yong-Un
- ㆍ 간행물명
- 大韓韓醫學會誌
- ㆍ 권/호정보
- 1999년|20권 3호|pp.18-26 (9 pages)
- ㆍ 발행정보
- 대한한의학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
This paper aims to determine the effect of CBW on the liver of mice treated with PQ (paraquat) examined by light and transmission electron microscope. Under light microscopic observations, the 2 days control showed mild congestion and necrosis of liver while those were manifest in the 7 days control. When electron microscopy was used, mitochondria and rough endoplasmic reticulum were dilated or destructed in the 2 days control and 7 days control, respectively. Under light microscopic observations, the 2 days experimental group did not show any hepatic damages while accumulation of glycogen granules in the cytoplasm was conspicuous in the 7 days experimental group. When electron microscopy was used, mitochondria and rough endoplasmic reticulum were less dilated in the 2 days experirrlental group. On the other hand, denaturation of cell organelles was not observed in the 7 days experimental group. These results suggest that CBW seems related with recovery from the PQ cytotoxity.