- 5,6-디플루오르 -2-아미노인단.염산염의 합성
- Synthesis of 5,6-difluoro-2-aminoindan.HCI
- ㆍ 저자명
- 마은숙
- ㆍ 간행물명
- 약학회지
- ㆍ 권/호정보
- 1999년|43권 6호|pp.751-755 (5 pages)
- ㆍ 발행정보
- 대한약학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
3,4-Difluoroamphetamine.HCI and 5,6-difluoro-2-aminoindan.HCI were synthesized as serotonergic agents. 3,4-Difluorobenzaldehyde was condensed with nitroethane and reduced with $LiAlH_4$ to obtain 3,4-difluoroamphetamine. And 5,6-difluoro-2-aminoidan.HCI was synthesizd through reactions of condensation with malonic acid, 10% Pd-C reduction, cyclization with polyphosphoric acid, oximation and catalytic hydrogenation.