In this article, we give an example of local derivation, that is not derivation, on the algebra F(x1,…, xn) of rational functions in x1, …, xn over an infinite field F, and show that if X is a set of symbols and {x1,…, xn} is a finite subset of X, n$geq$1, then each local derivation of F[x1,…, xn] into F[X] is a F-derivation and each local derivation of F[X] into itself is also a F-derivation.