This study was intended to use for the fatigue test in real structures and offer basic data for optimum welding structure design. To this purpose, we obserded the effect of the size and distance of plug welding hole on the static strength and fatigue life of welding structure under the shear/bending load for the improvement of fatigue life of plug welding joint between S/MBR and C/MBR in the lower structure of large bus. The result below is shown through this study. 1) Static and fatigue strength are strongly influenced by the direction of plug weld hole distributed. 2) Distances and diameters of the distributed holes are little dependent on the static strengths 3) In case of the directions of the distributed plug weld holes are vertical to the loading pin, fatigue life is dependent on distance of the distributed hole. 4) In case of the directions of the distributed plug weld holes are parallel to the loading pin, fatigue life is dependent on distance of the hole diameter.