A relation between composition and properties of Na2O-Al2O3-SiO2 glasses was investigated with application of the extreme vertical design. Properties investigated in this study include glass transition temperature density refractive index thermal expansion electrical conductivity bending strength and hardness, Most of the quadratic models fitted on property data were statistically significant. The properties estimated from the fitted equation agreed well with the measured properties. The estimated properties were compared with those reported by other investigators. Additional composition except for those of extreme vertices were needed to yield a slightly better result for the simple system such as a temary system. In addition an optimal composition on each property could be calculated by using optimization technique on result obtained from the fitted quadratic models.