Building a knowledge base effectively has been an important research area in the expert systems field. A variety of approaches have been studied including rules, semantic networks, and frames to represent the knowledge base for expert systems. As the size and complexity of the knowledge base get larger and more complicated, the integration of knowledge based with database technology cecomes more important to process the large amount of data. However, relational database management systems show many limitations in handing the complicated human knowledge due to its simple two dimensional table structure. In this paper, we propose Object-Oriented Knowledge Store (OOKS), a knowledge base model on the basis of a frame sturcture using an object-oriented database. In the proposed model, managing rules for inferencing and facts about objects in one uniform structure, knowledge and data can be tightly coupled and the performance of reasoning can be improved. For building a knowledge base, a knowledge script file representing rules and facts is used and the script file is transferred into a frame structure in database systems. Specifically, designing a frame structure in the database model as it is, it can facilitate management and utilization of knowledge in expert systems. To test the appropriateness of the proposed knowledge base model, a prototype system has been developed using a commercial ODBMS called ObjectStore and C++ programming language.