It is known from the previous study on the behavior of sharter single pile during simulated seaquake induced by the vertical component of earthquake that the compressive capacity and the soil plugging resistance of single open-ended pipe pile were completely degraded. But, the capacity of single open-ended pipe pile with greater penetration and the capacity of piles group with shorter penetration were expected to be stable after seaquake motion. In this study, first single pile, 2-pile or 4-pile groups with several simulated penetrations were driven into the calibration chamber with saturated fine medium sand and the compressive load test for each installed pile or pile groups was performed. Then, about 95% compressive load of the ultimate capacity was applied on the pile head during the simulated seaquake motion. Finally, to confirm the reduction of pile capacity during the simulated seaquake motion, the compressive load test for each single pile or pile groups after seaquake motion was performed. During the simulated seaquake, compressive capacities of single open-ended pipe pile and piles group installed in shallow sea were not decreased. But, the stability of open-ended pile installed in deep sea was depended on the pile penetration depth. So, single open-ended pile with greater penetration of 27 m was stable, and 2-pile and 4-pile groups with penetration more than 13m were stable. But, 2-pile groups with penetration of 7m was failed, and the compressive capacity of 4-pile groups with penetration of 7m was degraded about 15%.