This paper evaluates forty different dispatching rules with respect to twenty different performance measures of job shop scheduling under seven levels of workload imbalance. Computer simulation is used as a tool to determine rankings of the dispatching rules for a given workload imbalance. The experiments results show rankings of dispatching rules are different in the job shop with unbalanced machine workloads. As variations of workload imbalance increase from 7% to 78%, the performance of dispatching rules is gradually deteriorated in measure related to completion time and due date. These results guide scheduling practitioners not only to choosing dispatching rules but also to developing the model of facility investment for workload balance, when there are different levels of workload imbalance.