In this paper, we propose a cardioangiography sequence image coding scheme which use a subtraction between initial image and current frame inserted contrast dye. Stable regions are obtained by the multithreshold and meaningful region is extracted by the images with stable region. The image with meaningful region is classified into contour and texture information. Contour information is coded by contour coding. And texture information is approximated by two-dimensional polynomial function and each coefficients is coded. Experimental results confirm that the sequence of cardioangiography are well reconstructed at the low bit rate (0.02∼0.04 bpp) and high compression ratio.