This study was conducted to evaluate the ventilation to remove gases, vapor and particles of environmental tobacco smoke(ETS) in a closed room. The ventilation rate choosed were 0.445 ㎥/min, 0.528 ㎥/min, and 0.625 ㎥/min. ETS components measured were total suspended particle(TSP), ultraviolet particulate matter(UVPM), fluorescent particulate matter(FPM), solanesol, carbon dioxide($CO_2$), carbon monoxide(CO), nicotine, and 3-ethenylpyri-dine(3-EP). The concentration of ETS components measured rapidly decreased as increasing ventilation rate, but the removal efficiency by ventilation was different from each ETS compounds. The $CO_2$, and CO, gaseous components of ETS, were dominant components to be removed from the room by ventilation. The ventilation with 0.528 ㎥/min for 1 hr was enough to remove over 99% of those gaseous components. Nicotine and 3-EP needed the ventilation for 2 hrs to reduce over 95 % of those components. As the same ventilation rate, 99 % of TSP and solanesol concentration were removed from the room within 2 hrs, UVPM and FPM concentration decreased 90 %.