A value can be placed on the integrated science curriculum in terms of producing an insight into solving the routine problem. From such a point of view, the comprehensive concepts which explain the extensive natural phenomena were defined as the integrated themes in this study, and the contents of the integrated science curriculum were developed, as the understanding of the contents focused on the integrated theme enables us to be productive and have an insight. Through analyzing teaching materials, programs and curriculums in relation to the integrated science, five concepts of system, interaction, harmony and balance, structure and function, and circulation were established as the integrated themes, and the nature of each integrated theme was examined. Next, in accordance with the integrated theme, the content of the integrated science curriculum,which are deeper in aspect of the integration level than that of the current science of middle school, were developed. The content of the integrated science curriculum which was proposed in this study is of great significance. in that they provide new perspectives related to our current science curriculum.