Until 1993, Nanji landfill has been the main solid waste treatment facility for Seoul, which is the capital of Korea. Since the landfill has not been properly lined, soil and ground water around the landfill has been contaminated. Due to the proximity, it has been speculated that the water quality of the Han River would have been also influenced by the leachate. In order to illuminate this, HELP model to estimate the quantity of the leachate from Nanji landfill and RMA model to simulate the change of water quality in Han River were applied in this research. The result indicates that the quantity of leachate from Nanji landfill has been overestimated by previous works and it was due to the failure to consider the water storage capacity of the landfill. The effect from Nanji landfill leachate on the water quality, in terms of COD input, proves to be smaller than those from other tributaries and influents to the River and the effect is larger when the flow of the River is reversed due to the tide.