We present a new approach to the analysis of mobile cellular communication systems under the environment of mixed platforms adopting a guard channel scheme. We assume general cell residence time distributions according to platform-types. Our system model is based on a heterogeneous M/G/c loss system with customer-dependent guard channels, where heterogeneous customers with different service time distributions have different numbers of their own guard channels. We develop the general formula of steady state probabilities for the heterogeneous M/G/c loss system with customer-dependent guard channels. The mean channel occupancy times of new and handoff calls are rigorously derived under a general setting. Finally, our numerical results show that the blocking probability and the forced termination probability are sensitive to the cell residence time distributions.