저자들은 특징적인 흉부전산화 단층촬영 소견을 보이는 폐포단백증 환자를 폐조직 생검으로 확진하여 전폐 세척술로 임상적 호전을 얻은 2예를 문헌고찰과 함께 보고하는 바이다.
Pulmonary alveolar proteinosis (PAP) is a disorder in which an insoluble, proteinaceous material, rich in phospholipid, is deposited in alveoli and bronchioles. Several cases were reported since 1986, and the numbers of patients is increasing in Korea. Although the pathogenesis and causative treatment of PAP is not well known, whole lung lavage is the only consistently successful treatment. We report 2 cases of PAP which were confirmed by open lung biopsy with electron microscopy and clinically improved by whole lung lavage with a review of literature.
