Forty healty patients (15 males and 25 females) between 19 and 45 years of age with mandibular impacted third molar were selected for this tudy. A visual analog scale from 0 to 100 was used on the day of the procedure and on the first postoperative day for patient pain assessment. 1. In comparative study according to anesthesia, preoperative medication, depth of impacted teeth and gender, there were a variable range of pain and no significant differences statistically. 2. Intraoperative pain was the highest in the 2nd decade and first postoperative pain was the highest in the 3rd decade (P=0.0398) 3. Intraoperative and postoperative pain of operative duration below 10 minutes were the lower than that between 11 to 20 minutes (P=0.0398)