The purpose of this study was to investigate the factors influencing health promoting behavior and quality of life in the nursing students, to provide the basic data for health promoting intervention in order to improve quality of life. The subjects of this study were 199 nursing students, living in M city, during the period from May 18 to 25, 1999. The instruments for this study were the health promoting behavior scale developed by Walker et al.(1987), the quality of life scale by Ro(1988), the self efficacy scale by Sherer(1982), the health locus of control scale by Wallston et al. (1978) and the self esteem scale by Rogenberg(1965). The data were analyzed using descriptive statistics, Pearson correlation coefficients, stepwise multiple regression, t-test, ANOVA. The results of this study are as follows; 1. The health promoting behavior showed significant positive correlation with self efficacy, self esteem, internal health locus of control and quality of life. 2. The quality of life showed significant positive correlation with self efficacy, self esteem, internal health locus of control. 3. Stepwise multiple regression analysis revealed that the most powerful predictor of health promoting behavior was self efficacy. A combination of self efficacy, self esteem, health locus of control and quality of life accounted for $41\%$ of the variance in health promoting behavior. 4. Stepwise multiple regression analysis revealed that the most powerful predictor of quality of life was self esteem. A combination of self esteem, self efficacy and health promoting behavior accounted for $40\%$ of the variance in quality of life. Based on the above findings, it is suggested to develop nursing intervention to improve Self Efficacy, Self Esteem of nursing students enhance health promoting lifestyle.