구기자나무의 부위별 물추출물이 LPS (lipopolysaccharide) 및 Con A (concanavalin A)에 의한 마우스의 비장세포 증식능에 미치는 영향을 시험한 결과 부위별 면역 활성중 과실에서 의 No mil 처리구에서는 $0.1mg/ml{sim}0.5mg/ml$ 농도에서, LPS 처리구에서는 $0.01mg/ml{sim}0.1mg/ml$의 농도에서 B-cell (체액성 면역)의 분열증식을 촉진시켰다. 잎과 뿌리는 LPS 처리구에서 0.1mg/ml 까지 비장세포의 분열증식을 촉진시켰으며 Con A 처리구에서는 T-cell (세포성 면역)의 증식효과가 없었다.
To evaluate the biological effects of boxthorn (Lycium chinense Mill.) extracts on the immune response systems, the mitogenic effects were tested by LPS (lipopolysaccharide) and Con A (concanavalin A) using water extracts from various parts of Lycium chinense Mill. The proliferation of B-lymphocytes which were activated by the mitogen, LPS, was markedly increased in the concentration of 0.1mg/ml to 0.5mg/ml, but inhibited in more than 0.5mg/ml. It increased only proliferation of B-lymphocytes but not that of T-lymphocytes by Con A. There was no difference between boxthorn species in immune response. Water extracts of various parts in boxthorn enhanced the humoral immune response which was related to B-lymphocytes.
