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Two p-Terphenyls from Mushroom Paxillus panuoides with Free Radical Scavenging Activity
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  • Two p-Terphenyls from Mushroom Paxillus panuoides with Free Radical Scavenging Activity
  • Two p-Terphenyls from Mushroom Paxillus panuoides with Free Radical Scavenging Activity
저자명
Yun. Bong-Sik,Lee. In-Kyoung,Kim. Jong-Pyung,Yoo. Ick-Dong
간행물명
Journal of microbiology and biotechnology
권/호정보
2000년|10권 2호|pp.233-237 (5 pages)
발행정보
한국미생물생명공학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

As part of a continuing investigation to identify free radical scavengers from the fruit bodies of basidiomycetes, we isolated two p-terphenyl compounds, designated as PAl and PA2l, from cethanolic extract of the fruit body of Pasillus panuoides. The methanolic extract was processed by ethyl acetate extraction and silica gel column chromatography to yield two active fraction. PAl was obtained from one of the fractions through Sephadex LH-20 and silica gel column chromatographies and reverse-phase HPLC. The other fraction was purified by Sephadex LH-20 and reverse-phase column chromatographies to produce PA2. The compounds PA1 and PA2 were identified as leucomentin-4 and leucomentin-2, respectively, on the basis of various spectroscopic analyses. These compounds exhibited strong inhibitory activities against lipid peroxidation in rat liver microsomes with IC_{50}$ values of 0.10 and $0.06{;}mu extrm{g}ml$, respectively.