The purpose of this study is to investigate the effect of NIE instruction in learning mathematics. There are two groups. The one group is an experimental group which is assigned to use NIE in learning mathematics for 10 weeks. The other group is a controlled group which is received only ordinary teaching methods. The results of this study are as follows. 1. There is no significant difference in learning achievement between the experimental group and the controlled group in significant level 0.05. 2. There are some difference in mathematical disposition between two groups. That is, the students of experimental group learned NIE are not changed in mathematical disposition. However, the other group takes on negative attitude in a mathematical disposition. Considering that as the students go up higher grade, their mathematical disposition become negative, using NIE in mathematics education is valuable to prevent the negative disposition to the mathematics. 3. There are some difference between two groups in the open-ended problem test in significant level 0.05. Although using NIE has little effects in the ordinary test methods, NIE has some effects in the test which require communication ability.