The roughness effects are very important due to the presence of interacting asperities in partial lubrication regime. An average Reynolds equation using flow factors is very useful to determine the effects of surface roughness on mixed lubrication. In this paper, the pressure flow factors for surfaces having Gaussian and non-Gaussian distribution of roughness height are evaluated in terms of various kurtosis. The effect of kurtosis on pressure flow factors is investigated using random rough surface generated numerically. The pressure flow factor increases with increasing kurtosis in mixed lubrication regime (h/$sigma$<3). As h/$sigma$ increases, the pressure flow factors approach to 1 asymptotically regardless of kurtosis.