Work performance and human error are complicated phenomena so that it is very difficult to grasp the true nature of them. However, Event Related Potential (ERP) may give a clue to them because human brain reflects diverse psychophysiological process. In the present study, the possibility of ERP application to the ergonomic area was evaluated in view of grasping error symptoms. For that purpose, the subjects were asked to count specific characters in a random character matrix on a computer monitor, and their ERP was compared with their performance data. Based upon the results, the amplitude of P300 was not so high as that in the case of the Odd Ball tasks, correct response corresponded with stable ERP with high P300 amplitude whereas wrong response did with unstable, fluctuating ERP with low P300 amplitude. Those results coincided with the work performance, and it was concluded that 3-wave fluorescent with illumination level of 800 lux would be recommendable for the counting task in concern. Conclusively, ERP including P300 might supply an objective clue to the problem of human errors in cognitive process.