The famous US quality management expert J. M. Juran pointed out on the American Quality Congress of ASQC in 1994, that the 20th century is a century of productive force and the 21st century would be a century of quality. In the past dozens of years; science and technology have made rapid progress. Take electronic products for example, the non-conformity rate has dropped from 1%($10^{-2}$) and 1%($10^{-3}$) to ppm (parts per million, $10^{-6}$), even to ppb (parts per billion, $10^{-9}$). Such a low non-conformity rate can be called the super strict quality requirements of products of the $21^{st}$ Century. Super strict quality requirements can cause a series of new changes: Therefore, super strict quality requirements are unavoidable to produce significant influences to the industry of the $21^{st}$ century. This paper analyzed these influences and pointed out that which quality sciences must be paid attention to first.