Nowadays, domestic hospital business is under the great threat from the environmental changes caused by the entrance of foreign hospitals and the technical changes related to information systems. In such a situation, to enhance the competitive edge of a hospital, it is needed to set up a competitive strategy and to construct an efficient information systems to back up the competitive strategy. If the hospital information systems(HIS) is consistent with a competitive strategy backing up, the competitive force of a hospital will be enhanced. For this respect, the influence of the competitive strategy and HIS construction environments on the performance of HIS was examined. The results suggested that if a HIS should be newly constructed or should be restructured, it is necessary to select construction environments of HIS such as physical environments, development methods and development tools to support functional strategy effectively based on the competitive strategy adopted by a hospital.