Nowadays, after beginning of 21 centuries, owing to simplify market, the world is in the era of an influx of new paradigm that requires infinite competition. The manufacturing industries of Korea are in need of casting off high cost and low efficiency structure. The forfeiture of competition is resulted from the lost of level in quality of product. Today, the achievement of competitive product quality is coming from the following factors, that is., quality control, quality of service, marketing, human resources, finance, etc., together with process management. While Six Sigma, a newly introduced method to achieve process qualify outcome by sector of enterprise, is now being enjoyed a high reputation as a key device for competition by superiority enterprises in the United States, it has not been introduced sufficiently in the domestic enterprises yet. In our research, we, first of all, organized systematically the materials being released up to now. Furthermore, we looked over case studies of the American enterprises that apply Six Sigma strategy very successfully. Finally, we discussed the situation of domestic enterprises which are about to importing Six Sigma strategy as well as main causation of success by adopting it. While the enterprises approach Six Sigma strategy not in the way of on time and short term but in the way of long term, consistent renovation and persistent innovation we can assure that they will produce the highest quality and globally competitive products which are second to none.