Two new bisbenzylisoquinoline alkaloids tiliacosine (1) and tiliasine (2) were isolated from the leaves of Tiliacora racemosa Colebr.. The structures of these alkaloids were established on the basis of spectral evidence and by the correlation of their $^1H-NMR$ spectral data with those of the congeners N-methyltiliamosine (3), tiliamosine (4) and tiliacorine (5).