Sutures support wound healing during the initial phase. As the tensile strength of a wound increases, the need for the presence of sutures becomes less important. For this reason, absorbable suture materials have been sought. Nowadays, commonly used suture materials are Chromic Catgut, Coated Vicryl, and PDS. Among these materials, Coated Vicryl is the most popular. Studies were conducted to compare the handling properties, reliability of knots, wound healing, and tissue reactivity(Inflammation, Fibroblast proliferation, Collagen deposition, Giant cell reaction, Absorption) between AILEE vicryl and ETHICON vicryl. We used twelve purebred New Zealand white rabbits, and biopsied the tissue at three, seven, fourteen, and thirty days post implantation. The results showed that both were supple and easy to handle and tie, and gross and histologic differences were not apparent.