In order to study the anti-stress effect of hyangbujapalmultang, several measures of stress, including body weight changes, organ weight changes and catecholamine changes. The following result have been obtained: 1. The weight loss of contol group was $28.5{pm}1.8g$, that of sample group was $20.3{pm}1.6g$. This differance was statistcally significant. 2.The organ weight(Liver,Spleen,Kidney,Adrenal gland) was the only significant change in the spleen, in sample group comparing to control group. 3. The norepinephrine contents of control group was $695.5{pm}22.7pg/ml$, that of sample group was $607.4{pm}21.7pg/ml$. This shows significant difference in sample group comparing to contol group. 4. The epinephrine contents of control group was $212.8{pm}9.8pg/ml$, that of sample group was $182.6{pm}8.4pg/ml$. This shows significant differance in sample group comparing to control group. 5. The dopamine contents of control group was $504.5{pm}31.3$, that of sample group was $463.4{pm}27.8pg/ml$. This shows the value decreased, but none of it is significant. Based on avove results, it may be conculed that hyangbujapalmultang has anti-stress effects.