A methodology for enhancing the bond strength of a coating layer with a support has been established in preparing low-pressure reverse osmosis mO) hollow fiber which would experience shear badly in flowing feed un it. Prior to coating process, the support membrane, ultrafiltratiun polysulfone(PS) hollow fibers was pretreated with a reaction solution containing glutaraldehyde (GAl which has a good affinity to the suppurt membrane material as well as a reactivity to some of the cunstituents of cuating layer subsequently formed on the support by interfacial polymerization. Therefore, the reactant GA distributed unifonnly over the support layer through the pretreatment could provide a strong adhesive bond between the coating layer and the support, sticking fast to the support membrane through physical bond and, at the same time, connecting its functional group with the coating laycr by chemical bonding. Due to the strong adhesive bond, the resulting hollow fiber membrane showed an excellent long-tcnn stability in pcnneation.