The purpose of this study is to develop multifunctional fibers by sticking cinnamon microcapsules on cotton knit. The prepolymer was made from urea-formaldehyde for usage of wall materials of microcapsules. The parameters for adoptable condition are 5000rpm of agitation speed, 1% of dispersions concentration according to the observation with SEM and particle analyzer. The Antimicrobial activity of cotton knit treated with capsule was increased greatly and maintained on the laundering cycle.