Liposome-amino acid conjugates were prepared using dipalmitolyphosphatidylcholine(DPPC) and hydrophobically modified asparagine. A microdialyzer was used to measure glucose diffusion. The glucose binding affinity of DPPC-ODA-asparagine liposomes higher than that of DPPC liposomes and distilled water. The size of DPPC-ODA-asparagine was approximately 75-150 nm. Cholesterol increased the stability of liposomes, and reduced the size of liposome particles.