The biological activities of wastewater and sludge taken from the wastewater treatment process of Hyangnam pharmaceutic factories in Hwaseong, Kyeonggi-Do was measured using a respirometer. Oxygen uptake rate (OUR) was used as a tool for measuring biological activity. OUR was measured for varying amounts of sludge and organic chemicals in wastewater, and its toxicity was evaluated. Maximum OUR was observed as 61, 75, and 89 mg O$_2$/L/hr when sludge was added as 3, 5, and 10% of total volume, respectively. When the concentration of organic chemicals was changed to 1,486, 337, and 164 mg COD/L, maximum OUR was 53, 13, 8 mg O$_2$/L/hr, respectively. The toxicity test results showed that there seemed that there seemed to be no observable toxic effect on microbes in pharmaceutic wastewater.