The present paper presents the experimental results of pressure drip of water flow in annuli with spirally corrugated inner tubes in the turbulent flow regime. To understand the underlying physical phenomena responsible for heat transfer enhancement, pressure drop data documented elsewhere are combined to compare with those obtained from the present experiment for the Reynolds numbers of 1,000 to 8,000. Friction factors were found to be functions of trough depth, pitch and angle, and the annulus radius ratio. Friction factor increases in the spirally fluted tubes were larger than those in the corrugated tubes.