This paper is concerned with the development of a GIS-based distribution system with service consideration. The proposed model could be used for a wide range of logistics applications in planning, engineering and operational purpose for logistics system. This research addresses the formulation of those complex prob1ems of two-echelon logistics system to plan the incorporating supply center locations and distribution problems based on GIS. We propose an integrated logistics model for determining the optimal patterns of supply centers and inventory allocations (customers) with a three-step sequential approach. 1) First step, Developing GIS-distance model and stochastic set-covering program to determine Optimel pattern of supply center location. 2) Second step, Optimal sector-clustering to support customers. 3) Third step, Optimal vehicle rouse scheduling based on GIS, GIS-VRP In this research we developed GUI-tree program, the GIS-VRP provide the vehicle to users and freight information in real time. We applied a set of sample examples to this model and demonstrated samp1e results. It has been found that the proposed model is potentially efficient and useful in solving multi-depot problem through examples. However the proposed model can provide logistics decision makers to get the best supply schedule.