Seals in a universal joint bearing are important components reinforcing lubrication performance by holding lubricant and preventing infiltration of dust, moisture, etc.. There is a great difference in seal performance according to seal shape and bonding position. Therefore, in this study, as for both the lip type seal and the O-ring type seal, FE analysis is conducted using Mooned-Rivlin Model. The results show that O-ring type seal does not have any effect of misalignment angle compared with lib type seal, which is more profitable.