In this study, an optimum design algorithm using efficient reanalysis is proposed for seismic design of Reinforced Concrete (RC) piers. The proposed algorithm for optimization of RC piers is based on efficient reanalysis technique. Considering structural behavior of RC piers, the other approximation technique such as artificial constraint deletion is introduced to increase the efficiency of optimization. The efficiency and robustness of the proposed algorithm including the proposed reanalysis technique is demonstrated by comparing it with a conventional optimization algorithm. A few of design examples are optimized to show the applicability of the proposed algorithm.