Three-dimensional and unsteady flow analysis is a practical target of high performance computation. As recently advances of computers, a numerical prediction by the large eddy simulation (LES) are introduced and evaluated for various engineering problems. Its advanced methods for the complex turbulent flows are discussed by several examples applied for aerodynamic designs, analysis of fluid flow mechanisms and their interaction to complex phenomena. These results of time-dependent and three-dimensional phenomena are visualized by interactive graphics and animations.