DUPIC (Direct use of spent PWR fuel in CANDU reactors) nuclear fuel is a CANDU fuel fabricated remotely from spent PWR fuel materials in a hot cell. The soundness of the end closure welds of nuclear fuel elements is an important factor for the safety and performance of nuclear fuel. To evaluate the soundness of the end closure welds of DUPIC fuel element, a precise X-ray inspection system is developed using a micro-focus X-ray generator with an image intensifier and a real time camera system. The fuel elements made of Zircaloy-4 and stainless steel by an Nd:YAG laser welding and a TIG welding aye inspected by the developed inspection system. The soundness of the welds of the fuel elements was confirmed by the X-ray inspection process, and the irradiation test of DUPIC fuel elements has been successfully completed at the HANARO research reactor.