This paper is an inquiry into the patterns of technological innovation of bio - industry in Korea in comparison with the worldwide patterns. In another words, this study wants to check whether the patterns of technological innovation of bio - industry in Korea differ front those in advanced countries or not. The comparison is based on the theory of science - based industry asserted by Seol (2001) and Cho (2001). There are no specific difference in the patterns of technological innovation such as science - based innovation, capitalization of science, industries leading by scientific fields, the importance of venture firms for commercialization, high level of R&D expense to sales. Also the order of fields by size is similar to worldwide patterns. But the size of microbiology is bigger than that of worldwide patterns. The strength in microbiology may be the country specific features of Korea, like platform technology of Germany.