In this paper, we suggests a algorithms of recognizing the disease region by extracting particular organ from medical image. This method can extract liver region in spite of input image including many organs and charged format by using multi-threshold of feed-back-structure for segmentation liver region, and suggest the recognition of disease region in extracted liver, using multi-neural network structured by RBF and BP, overcoming the defect of single-neural network. The algorithm in this paper is proficient in adaptation for a multi form change of input medical image. This algorithm can be used at tole-medicine through automatic recognition after recognizing of the disease region by real-tire medical Image.